This will prevent Mom's hand from attacking and causing damage before it can be dodged. A common and effective strategy is to stay in the center area of the room. All enemies and body parts will be destroyed when her health is brought to zero. Mom, like other bosses, has a single health bar that depletes when any of her body parts are damaged. Mom can have up to 4 additional enemies assisting her during the fight. Mom's Flesh: A lump of flesh that will appear and summon an enemy next to it.(Note: Mom's red champion version (see below) will fire a triple blood shot from the eye)

The eye does not attack or spawn enemies, offering a short period of time in which to damage Mom. Mom's Eye: Periodically appears in one of the four doorways.

However, this attack happens very quickly and is much harder to dodge than the foot. Mom will stop stomping for a short period if this attack is used.

Mom's Hand: An alternate attack used when Isaac is too close to a door between stomps.

This attack can damage other enemies in the room and even Mom herself, if the foot lands on Flesh or an Eye. Deals damage in a radius approximately equivalent to the shadow that it casts before contacting.

Mom's Foot: Mom's main attack, used when Isaac is not near any of the four doors.

Binding of isaac revelations chapter 2